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Journal Club

Influence of Diet and Probiotic Bacteria on Intestinal Barrier Function
The permeability of the intestinal epithelial barrier plays a significant role in an individual's systemic exposure to LPS and other bacterial toxins. The complex relationship between diet and intestinal permeability is not entirely clear, however the article reviewed here presents evidence that a probiotic bacteria, L. gasseri SBT2055, may be able to improve intestinal permeability. This research can lead to new strategies for treating metabolic disorders like obesity. Read More
Review: Therapeutic Effect of L. helveticus (SBT2171) on Collagen-Induced Arthritis
Review of Yamashita et al. (2017) that highlights the therapeutic effect of L. helveticus (SBT2171) on collagen-induced arthritis in mice. Read More
The Hygiene Hypothesis, the Naïve Immune System and House Dust Mites
A look at the implications of the hygiene hypothesis in the development of treatments for allergic hypersensitivity to common aeroallergens Read More
Gut Microbiome Composition Influences Collagen-Induced Arthritis Susceptibility in DBA1 Mice
A review of an article by Liu et al. (doi: 10.1038/srep30594) that investigates the relationship between gut microbiome composition and susceptibility to collagen-induced arthritis in DBA1 mice. Read More
Microbiome LPS Heterogeneity Contributes to Autoimmunity
A look at how LPS heterogeneity contributes to the development of type 1 diabetes. Read More
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