Collagen-induced arthritis (CIA) can be induced in various strains of rats by immunization with heterologous type II collagen. In general, 50-60% of antibodies against the collagen used for immunization cross-react to autologous rat type II collagen. It is important to determine antibody levels to the heterologous type II collagen used for immunization and to autologous collagen to correlate IgG antibody levels, as well as IgG subtype (IgG1 and IgG2a) levels, with the development and severity of arthritis in the rat CIA model.
Rat Anti-Collagen IgG Antibody Assay Kit
Rat Anti-Collagen IgG1 Antibody Assay Kit
| Product | Catalog # | Price (USD) |
| Rat Anti-Bovine Type II Collagen IgG1 Antibody Assay Kit | 20421T | 445.00 |
| Rat Anti-Porcine Type II Collagen IgG1 Antibody Assay Kit | 20431T | 445.00 |
| Rat Anti-Rat Type II Collagen IgG1 Antibody Assay Kit | 20441T | 472.00 |
Rat Anti-Collagen IgG2a Antibody Assay Kit
| Product | Catalog # | Price (USD) |
| Rat Anti-Bovine Type II Collagen IgG2a Antibody Assay Kit | 20422T | 445.00 |
| Rat Anti-Porcine Type II Collagen IgG2a Antibody Assay Kit | 20432T | 445.00 |
| Rat Anti-Rat Type II Collagen IgG2a Antibody Assay Kit | 20442T | 472.00 |
Rat Anti-Type I and Type II Collagen IgG Assay Kit Protocol
Rat Anti-Type I and Type II Collagen IgG Assay Kit with TMB Protocol
Rat Anti-Type I and Type II Collagen IgG Subtype Assay Kit with TMB Protocol
A standard rat kit with one species of collagen will measure 39 samples. Each kit contains a reference standard and reagents to perform two partial assays. Customized kits to measure antibody levels against various species of type I and type II collagen can be custom ordered. Please contact us for ordering of these custom kits.