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Influence of Diet and Probiotic Bacteria on Intestinal Barrier Function
The permeability of the intestinal epithelial barrier plays a significant role in an individual's systemic exposure to LPS and other bacterial toxins. The complex relationship between diet and intestinal permeability is not entirely clear, however the article reviewed here presents evidence that a probiotic bacteria, L. gasseri SBT2055, may be able to improve intestinal permeability. This research can lead to new strategies for treating metabolic disorders like obesity. Read More
Introduction to Exosomes: Origin, Characteristics, and Isolation
A brief overview discussing the differences between exosomes and other extracellular vesicles, therapeutic potential of exosomes, and the difficulties in purifying exosomes. Read More
Review: Therapeutic Effect of L. helveticus (SBT2171) on Collagen-Induced Arthritis
Review of Yamashita et al. (2017) that highlights the therapeutic effect of L. helveticus (SBT2171) on collagen-induced arthritis in mice. Read More
New Product Alert: CD63, CD9, PD-1, PD-L1 Monoclonal Antibodies
For use in exosome and cancer research, Chondrex manufactures monoclonal antibodies against CD9, CD63, PD-1, PD-L1. Don't forget about our 50% trial discount! Read More
New Product Alert: Mouse Anti-HDM IgE Antibody Assay Kit
Chondrex offers a line of ELISA kits for characterizing the antibody response to House Dust Mite (HDM) antigens in mouse asthma models. Read More
The Hygiene Hypothesis, the Naïve Immune System and House Dust Mites
A look at the implications of the hygiene hypothesis in the development of treatments for allergic hypersensitivity to common aeroallergens Read More
Review: Naive CD4+ T-cells in Autoimmunity & Inflammation
A brief review covering the differentiation of helper T cell lineages and their implications in inflammation and autoimmune pathways. Read More
Tools to Study the Pathological Effect of Human Microbiota in Rheumatoid Arthritis
An overview of murine arthritis models ideal for studying the pathological effects of bacteria and bacterial toxins in the development of rheumatoid arthritis. Read More
Gut Microbiome Composition Influences Collagen-Induced Arthritis Susceptibility in DBA1 Mice
A review of an article by Liu et al. (doi: 10.1038/srep30594) that investigates the relationship between gut microbiome composition and susceptibility to collagen-induced arthritis in DBA1 mice. Read More
Microbiome LPS Heterogeneity Contributes to Autoimmunity
A look at how LPS heterogeneity contributes to the development of type 1 diabetes. Read More
ChonBlock: A Solution to False Positive Reactions in ELISA
An overview of non-specific reactions in indirect ELISA that can lead to false positive results. Read More
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