Chondrex Inc. is committed to supporting researchers around the world fight the COVID-19 pandemic. Recent publications have reported that severe cases of COVID-19 elicit a cytokine storm, which is defined as an excessive immune response to external stimuli (1,2). The cytokine storm elicits a complex pathogenesis which leads to severe health deterioration and increased mortality rate (1,2). Currently, therapies that can dampen the cytokine storm are of great interest (1-3), but more research is needed on these therapies in the context of COVID-19. Enzyme-linked immunosorbent assays (ELISAs) are a straightforward, cost-effective analytical tool that provides both the specificity and sensitivity required for the study of cytokine dynamics in COVID-19 research (4).
Chondrex Inc. provides high quality Cytokine Detection ELISA Kits and immunoassay buffers that can assist in SARS-CoV-2 research. Our ChonBlock ELISA Buffers are designed specifically to eliminate non-specific reactions that cause high background values in indirect ELISAs (13). The high blocking capacity of ChonBlock is ideal for assaying samples with unknown histories since high background values observed in some pathological conditions can lead to misinterpreted results (14,15). More information on how ChonBlock works, as well as an ELISA troubleshooting FAQ, can be found on our blog. If you have any questions about using ChonBlock in your assay or any questions about when your order can ship, please contact us.
Additionally, High-Mobility Group Box Protein 1 (HMGB1) has been suggested as a therapeutic target for COVID-19 (16). Our HMGB1 Detection Kit is a well referenced, reliable ELISA kit that can be used to study the role of HMGB1 in COVID-19.
The table below shows COVID-19 relevant research products Chondrex Inc. offers. This list has been carefully selected and relevant research publications have been referenced. Due to COVID-19 we are currently shipping on a reduced schedule, but we are prioritizing shipping for COVID-19 research. Please email us at firstname.lastname@example.org if you have any questions concerning shipping. If you would like to try one of the products, we offer 50% trial discounts for the first-time purchase of one of our products.
|Cytokine and Chemokine ELISA Detection Kits
References 1-3, 8-12
|Interleukin-6 (IL-6)||6802 & 6702||40 samples (duplicate)|
|Interleukin-1 Beta (IL-1β)||6805 & 6705||40 samples (duplicate)|
|Interleukin-2 (IL-2)||6811 & 6711||40 samples (duplicate)|
|Interleukin-10 (IL-10)||6806 & 6706||40 samples (duplicate)|
|Tumor Necrosis Factor Alpha (TNFα)||6801 & 6701||40 samples (duplicate)|
|C-C Motif Chemokine Ligand 2 (CCL2)||6821 & 6721||40 samples (duplicate)|
|C-C Motif Chemokine Ligand 5 (CCL5)||6822 & 6722||40 samples (duplicate)|
|Interferon Gamma (IFNγ)||6804 & 6704||40 samples (duplicate)|
High Mobility Group Box 1 (HMGB1) Detection
|HMGB1 Detection Kit||6010||40 sample (duplicate)|
ELISA Buffers and Plates
Dilution ELISA Buffer
|ChonBlockTM Detection Antibody Dilution Buffer||90681||100 mL|
|ELISA Plates w/ removable strips||9026||96-wells|