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Mouse - Anti-Type II Collagen Subtype Antibody Assay

Autoantibodies to type II collagen play a primary role in inducing autoimmune-mediated inflammatory arthritis in the CIA model, but autoantibodies are not always capable of inducing arthritis. In mice, complement fixable IgG2a and IgG2b subtype autoantibody levels are pertinent in the induction of arthritis, as well as their epitope specificity. In order to adequately study the pathological roles of antibodies to type II collagen, Chondre, Inc. provides mouse anti-collagen IgG subtype (IgG1, IgG2a, IgG2b, IgG2c, and IgG3) antibody assay kits for further detailed analysis of antibodies in the mouse CIA model.

Mouse Anti-Type II Collagen IgG1 Subtype Antibody Assay Kit

Collagen Coated Wells Chromagen Catalog # Price (USD)
Bovine II OPD 20321 397.00
Bovine II TMB 20321T 397.00
Chick II OPD 20311 397.00
Chick II TMB 20311T 397.00
Human II OPD 20351 428.00
Human II TMB 20351T 428.00
Mouse II OPD 20361 479.00
Mouse II TMB 20361T 479.00
Porcine II OPD 20331 397.00
Porcine II TMB 20331T 397.00

Mouse Anti-Type II Collagen IgG2a Subtype Antibody Assay Kit

Collagen Coated Wells Chromagen Catalog # Price (USD)
Bovine II OPD 20322 397.00
Bovine II TMB 20322T 397.00
Chick II OPD 20312 397.00
Chick II TMB 20312T 397.00
Human II OPD 20352 428.00
Human II TMB 20352T 428.00
Mouse II OPD 20362 479.00
Mouse II TMB 20362T 479.00
Porcine II OPD 20332 397.00
Porcine II TMB 20332T 397.00

Mouse Anti-Type II Collagen IgG2b Subtype Antibody Assay Kit

Collagen Coated Wells Chromagen Catalog # Price (USD)
Bovine II OPD 20323 397.00
Bovine II TMB 20323T 397.00
Chick II OPD 20313 397.00
Chick II TMB 20313T 397.00
Human II OPD 20353 428.00
Human II TMB 20353T 428.00
Mouse II OPD 20363 479.00
Mouse II TMB 20363T 479.00
Porcine II OPD 20333 397.00
Porcine II TMB 20333T 397.00

Mouse Anti-Type II Collagen IgG2c Subtype Antibody Assay Kit

Collagen Coated Wells Chromagen Catalog # Price (USD)
Bovine II OPD 20325 397.00
Bovine II TMB 20325T 397.00
Chick II OPD 20315 397.00
Chick II TMB 20315T 397.00
Human II OPD 20355 428.00
Human II TMB 20355T 428.00
Mouse II OPD 20365 479.00
Mouse II TMB 20365T 479.00
Porcine II OPD 20335 397.00
Porcine II TMB 20335T 397.00

Mouse Anti-Type II Collagen IgG3 Subtype Antibody Assay Kit

Collagen Coated Wells Chromagen Catalog # Price (USD)
Bovine II OPD 20324 397.00
Bovine II TMB 20324T 397.00
Chick II OPD 20314 397.00
Chick II TMB 20314T 397.00
Human II OPD 20354 428.00
Human II TMB 20354T 428.00
Mouse II OPD 20364 479.00
Mouse II TMB 20364T 479.00
Porcine II OPD 20334 397.00
Porcine II TMB 20334T 397.00

Mouse Anti-Type II Collagen IgG Subtype Assay Kit Protocol
Mouse Anti-Type II Collagen IgG Subtype Assay Kit with TMB Protocol
 

In order to adequately study the pathological roles of antibodies to type II collagen in mouse CIA model, it is important to determine individual IgG subtype autoantibody levels to mouse type II collagen as well as the antibody levels to the heterologous type II collagen used for immunization.

A standard mouse kit with one species of collagen will measure 39 samples. Each kit contains a reference standard and reagents to perform two partial assays. Customized kits to measure antibody levels to various species of type I and type II collagen can be custom ordered.