Type I hypersensitivity reaction mediated by IgE is a typical clinical
feature of allergic diseases, such as asthma, eczema, hay fever, and
urticaria. Chondrex provides mouse IgE anti-OVA monoclonal antibodies
and related kits for studying allergic diseases in vitro and in vivo.
Three types of IgE detection kits are available. These IgE detection
kits employ an identical IgE standard (Clone E-C1). Therefore, the
ratio of total IgE and ovalbumin (OVA) specific IgE in individual
samples is easily and accurately compared. In addition, rat anti-mouse
IgE monoclonal antibodies (Clone 345-2 and 77-1) used in these kits
react to both IgE
a and IgEb allotypes. Therefore,
separate assays for IgEa and IgEb allotypes are
not required.