Type I hypersensitivity reaction mediated by IgE is a typical clinical feature of allergic diseases, such as asthma, eczema, hay fever, and urticaria.  Chondrex provides mouse IgE anti-OVA monoclonal antibodies and related kits for studying allergic diseases in vitro and in vivo.

Three types of IgE detection kits are available.  These IgE detection kits employ an identical IgE standard (Clone E-C1).  Therefore, the ratio of total IgE and ovalbumin (OVA) specific IgE in individual samples is easily and accurately compared.  In addition, rat anti-mouse IgE monoclonal antibodies (Clone 345-2 and 77-1) used in these kits react to both IgE^a and IgE^b allotypes.  Therefore, separate assays for IgE^a and IgE^b allotypes are not required.